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Dose escalation timeline

Standard titration schedule for each GLP-1. Your prescriber may slow or pause steps based on tolerability — most people do.

Zepbound (tirzepatide)
  1. Week 1
    2.5 mg weekly
  2. Week 5
    5 mg weekly
  3. Week 9
    7.5 mg weekly
  4. Week 13
    10 mg weekly
  5. Week 17
    12.5 mg weekly
  6. Week 21
    15 mg weekly (max)

Tip: if nausea hits at any step, a common move is to hold the dose for another 4 weeks before escalating. Your prescriber decides, not this calculator.

For education only. Trial averages are population-level — your actual results will differ. Not medical advice.